Published Data Registry

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TitleAuthorsJournalPublication year
DOI
PMID
The adapted Activity-By-Contact model for enhancer-gene assignment and its application to single-cell data(Open Access) Hecker D, Behjati Ardakani F, Karollus A, Gagneur J, Schulz MHBioinformatics2023
The endothelial-enriched lncRNA LINC00607 mediates angiogenic function(Open Access) Boos F, Oo JA, (...), Leisegang MSBasic Research in Cardiology2023
Poison cassette exon splicing of SRSF6 regulates nuclear speckle dispersal and the response to hypoxia(Open Access) de Oliveira Freitas Machado C, Schafranek M, (...), Müller-McNicoll MNucleic Acids Res2023
Computational Methods to Study DNA:DNA:RNA Triplex Formation by lncRNAs(Open Access) Warwick T, Brandes RP, Leisegang MSNon-Coding RNA2023
A Tedious Journey: Cardiomyocyte Proliferation Requires More Than S-Phase Entry and Loss of PolyploidizationDing D, Braun TCirculation2023
The emerging landscape of non-conventional RNA functions in atherosclerosis(Open Access) Farina FM, Weber C, Santovito DAtherosclerosis2023
A universal model of RNA.DNA:DNA triplex formation accurately predicts genome-wide RNA–DNA interactions(Open Access) Warwick T, Seredinski S, (...), Brandes RPBrief Bioinform2022
High-throughput optical action potential recordings in hiPSC-derived cardiomyocytes with a genetically encoded voltage indicator in the AAVS1 locus(Open Access) Zhang F, Meier AB, (...), Dorn TFrontiers in Cell and Developmental Biology2022
Unravelling the impact of aging on the human endothelial lncRNA transcriptome(Open Access) Drekolia M, Talyan S, (...), Bibli SFrontiers in Genetics2022
HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex(Open Access) Leisegang MS, Bains JK, (...), Brandes RPNature Communications2022
Replication collisions induced by de-repressed S-phase transcription are connected with malignant transformation of adult stem cells(Open Access) Zhang T, Künne C, (...), Braun TNature Communications2022
Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2(Open Access) Oo JA, Pálfi K, (...), Brandes RPCell Reports2022
Gene Therapy and Cardiovascular DiseasesLu D, Cushman S, Thum T, Bär CAdv Exp Med Biol2022
Linking single nucleotide polymorphisms to signaling blueprints in abdominal aortic aneurysms(Open Access) Lim C, Pratama MY, (...), Ramkhelawon BScientific Reports2022
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants(Open Access) Aragam KG, Jiang T, (...), von Scheidt MNature Genetics2022
Quo Vadis? Immunodynamics of Myeloid Cells after Myocardial Infarction(Open Access) Moggio A, Schunkert H, Kessler T, Sager HBInt J Mol Sci2022
Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine(Open Access) Wu F, Li X, (...), Braun TNature Genetics2022
ADAR1 Prevents Autoinflammatory Processes in the Heart Mediated by IRF7(Open Access) Garcia-Gonzalez C, Dieterich C, (...), Braun TCirculation Research2022
Aging-regulated TUG1 is dispensable for endothelial cell function(Open Access) Gimbel AT, Koziarek S, (...), Boon RAPLoS One2022
Genetic and modifiable risk factors combine multiplicatively in common disease(Open Access) Pang S, Yengo L, (...), Schunkert HClinical Research in Cardiology2022
Modulation of pre-mRNA structure by hnRNP proteins regulates alternative splicing of MALT1(Open Access) Jones AN, Graß C, (...), Sattler MScience Advances2022
Calcium-Controlled Reactive Oxygen Species Afterburner Perpetuates Endothelial Damage After Radiation Therapy(Open Access) Brandes RP, Wittig IArterioscler Thromb Vasc Biol2022
Accelerating cardiovascular research: recent advances in translational 2D and 3D heart models(Open Access) Mohr E, Thum T, Bär CEuropean Journal of Heart Failure2022
Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression(Open Access) Georgieva AM, Guo X, (...), Braun TNature Communications2022
Orphan GPR26 Counteracts Early Phases of Hyperglycemia-Mediated Monocyte Activation and Is Suppressed in Diabetic Patients(Open Access) Kichi ZA, Natarelli L, Sadeghian S, Boroumand Ma, Behmanesh M, Weber CBiomedicines2022
Colchicine Impacts Leukocyte Trafficking in Atherosclerosis and Reduces Vascular Inflammation(Open Access) Meyer-Lindemann U, Mauersberger C, (...), Sager HBFrontiers in Immunology2022
The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm(Open Access) Kirchhof L, Fouani Y, (...), Jaé NNon-Coding RNA2022
Conformational Effects of a Cancer-Linked Mutation in Pri-miR-30c RNA(Open Access) Jones AN, Walbrun A, Falleroni F, Rief M, Sattler MJournal of Molecular Biology2022
Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs(Open Access) Kokot KE, Kneuer JM, (...), Boeckel JBasic Research in Cardiology2022
MicroRNAs as therapeutic targets in cardiovascular disease(Open Access) Laggerbauer B, Engelhardt SJ Clin Invest2022
Mechano-signaling via Piezo1 prevents activation and p53-mediated senescence of muscle stem cells(Open Access) Peng Y, Du J, (...), Braun TRedox Biology2022
Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors(Open Access) Poch CM, Foo KS, (...), Laugwitz KNature Cell Biology2022
The splicing‐regulatory lncRNA NTRAS sustains vascular integrity(Open Access) Fouani Y, Kirchhof L, (...), Jaé NEMBO reports2022
Neonatal injury models: integral tools to decipher the molecular basis of cardiac regeneration(Open Access) Costa A, Cushman S, Haubner BJ, Derda AA, Thum T, Bär CBasic Research in Cardiology2022
Generation of heterozygous (MRli003-A-5) and homozygous (MRli003-A-6) voltage-sensing knock-in human iPSC lines by CRISPR/Cas9 editing of the AAVS1 locus(Open Access) Zhang F, Meier AB, (...), Moretti AStem Cell Research2022
MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice(Open Access) Peters LJF, Baaten CCFMJ, (...), van der Vorst EPCBiomedicines2022
Exercise-Induced Long Noncoding RNAs As New Players in Cardiac Hypertrophy(Open Access) Makarewich CA, Thum TCirculation2022
miR-486 attenuates cardiac ischemia/reperfusion injury and mediates the beneficial effect of exercise for myocardial protectionBei Y, Lu D, (...), Xiao JMolecular Therapy2022
Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes(Open Access) Li L, Chen Z, (...), Schunkert HBasic Research in Cardiology2022
Generation of heterozygous (MRli003-A-3) and homozygous (MRli003-A-4) TRPM4 knockout human iPSC lines(Open Access) Zhang F, Meier AB, Lipp P, Laugwitz K, Dorn T, Moretti AStem Cell Research2022
Interdependence of Angiogenesis and Arteriogenesis in Development and Disease(Open Access) le Noble F, Kupatt CInt J Mol Sci2022
Cardiac remodelling – Part 1: From cells and tissues to circulating biomarkers. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of CardiologyGonzález A, Richards AM, (...), Bayés‐Genís AEuropean Journal of Heart Failure2022
Non-canonical features of microRNAs: paradigms emerging from cardiovascular diseaseSantovito D, Weber CNature Reviews Cardiology2022
Nicht kodierende Ribonukleinsäure im kardiovaskulären System(Open Access) Engelhardt S, Dimmeler S, (...), Zarnack KDer Kardiologe2022
Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques(Open Access) Egea V, Megens RTA, (...), Ries CCardiovasc Res2022
Development and characterization of anti-fibrotic natural compound similars with improved effectivity(Open Access) Kreutzer FP, Meinecke A, (...), Thum TBasic Research in Cardiology2022
A Non-Canonical Link between Non-Coding RNAs and Cardiovascular Diseases(Open Access) Natarelli L, Weber CBiomedicines2022
Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19(Open Access) Sala L, Leonov V, (...), Schwartz PJFrontiers in Physiology2022
Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome(Open Access) Meier AB, Raj Murthi S, (...), Wolf CMiScience2022
Endothelial Retargeting of AAV9 In Vivo(Open Access) Bozoglu T, Lee S, (...), Kupatt CAdvanced Science2022
MicroRNA-365 regulates human cardiac action potential duration(Open Access) Esfandyari D, Idrissou BMG, (...), Engelhardt SNature Communications2022
Human Macrophage Long Intergenic Noncoding RNA, SIMALR, Suppresses Inflammatory Macrophage Apoptosis via NTN1 (Netrin-1)Cynn E, Li DY, (...), Reilly MPArterioscler Thromb Vasc Biol2022
Emerging epigenetic therapies of cardiac fibrosis and remodelling in heart failure: from basic mechanisms to early clinical development(Open Access) McKinsey TA, Foo R, (...), Thum TCardiovasc Res2022
Functional RNA Dynamics Are Progressively Governed by RNA Destabilization during the Adaptation to Chronic Hypoxia(Open Access) Bauer R, Meyer SP, (...), Brüne BInt J Mol Sci2022
A circular RNA derived from the insulin receptor locus protects against doxorubicin-induced cardiotoxicity(Open Access) Lu D, Chatterjee S, (...), Thum TEur Heart J2022
Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function(Open Access) Klockner I, Schutt C, Gerhardt T, Boettger T, Braun TNature Communications2022
Integrative analysis of epigenetics data identifies gene-specific regulatory elements(Open Access) Schmidt F, Marx A, (...), Schulz MNucleic Acids Res2021
Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC)(Open Access) de Boer RA, Heymans S, (...), Thum TEuropean Journal of Heart Failure2021
Concomitant Activation of OSM and LIF Receptor by a Dual-Specific hlOSM Variant Confers Cardioprotection after Myocardial Infarction in Mice(Open Access) Lörchner H, Adrian-Segarra JM, (...), Pöling JInt J Mol Sci2021
Ryanodine Receptors Matter for Cardiac Function in Duchenne Muscular Dystrophy(Open Access) Kupatt C, Bozoglu TJournal of the American College of Cardiology2021
Polygenic risk for coronary artery disease in the Scottish and English population(Open Access) Yang C, Starnecker F, (...), Schunkert HBMC Cardiovascular Disorders2021
Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load(Open Access) Kaneshige A, Kaji T, (...), Fukada SCell Stem Cell2021
Generation of heterozygous (MRli003-A-1) and homozygous (MRli003-A-2) MYH10 knockout human iPSC lines(Open Access) Zhang F, Meier AB, Laugwitz K, Dorn T, Moretti AStem Cell Research2021
The long non-coding RNA NRON promotes the development of cardiac hypertrophy in the murine heartHoepfner J, Leonardy J, (...), Thum TMolecular Therapy2021
Long non-coding RNAs: novel regulators of cellular physiology and function(Open Access) Oo JA, Brandes RP, Leisegang MSPflügers Archiv - European Journal of Physiology2021
Locus-Conserved Circular RNA cZNF292 Controls Endothelial Cell Flow Responses(Open Access) Heumüller AW, Jones AN, (...), Dimmeler SCirculation Research2021
Non-coding RNAs: key regulators of reprogramming, pluripotency, and cardiac cell specification with therapeutic perspective for heart regeneration(Open Access) Hunkler HJ, Groß S, Thum T, Bär CCardiovasc Res2021
Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome(Open Access) Krane M, Dreßen M, (...), Moretti ACirculation2021
Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization(Open Access) Fasolo F, Jin H, (...), Maegdefessel LCirculation2021
Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart(Open Access) Valussi M, Besser J, (...), Braun TScience Advances2021
Risk Prediction of Cardiovascular Events by Exploration of Molecular Data with Explainable Artificial Intelligence(Open Access) Westerlund AM, Hawe JS, Heinig M, Schunkert HInt J Mol Sci2021
1H, 13C and 15N assignment of stem-loop SL1 from the 5'-UTR of SARS-CoV-2(Open Access) Richter C, Hohmann KF, (...), Wacker ABiomolecular NMR Assignments2021
Parallel Murine and Human Aortic Wall Genomics Reveals Metabolic Reprogramming as Key Driver of Abdominal Aortic Aneurysm Progression(Open Access) Gäbel G, Northoff BH, (...), Lindeman JHNJournal of the American Heart Association2021
Increased presence of nuclear DNAJA3 and upregulation of cytosolic STAT1 and of nucleic acid sensors trigger innate immunity in the ClpP-null mouse(Open Access) Maletzko A, Key J, (...), Auburger Gneurogenetics2021
Coronary Artery Disease Genetics Enlightened by Genome-Wide Association Studies(Open Access) Kessler T, Schunkert HJACC: Basic to Translational Science2021
Understanding Arteriosclerosis 2.0: Making Sense of Genetic Variants with scATAC(Open Access) Brandes RP, Gilsbach RCirculation Research2021
Genetics of coronary artery disease in the post‐GWAS era(Open Access) Chen Z, Schunkert HJournal of Internal Medicine2021
Lenvatinib halts aortic aneurysm growth by restoring smooth muscle cell contractility(Open Access) Busch A, Pauli J, (...), Maegdefessel LJCI Insight2021
AntimiR-132 Attenuates Myocardial Hypertrophy in an Animal Model of Percutaneous Aortic ConstrictionHinkel R, Batkai S, (...), Kupatt CJournal of the American College of Cardiology2021
Not all myocardial infarctions are created equal: The potential of circulating microRNAs to discern coronary artery dissection(Open Access) Santovito D, Weber CEBioMedicine2021
Cis-epistasis at the LPA locus and risk of cardiovascular diseases(Open Access) Zeng L, Moser S, (...), Schunkert HCardiovasc Res2021
Progressive stretch enhances growth and maturation of 3D stem-cell-derived myocardium(Open Access) Lu K, Seidel T, (...), Tomasi RTheranostics2021
Non-coding RNAs in Cardiac Regeneration(Open Access) Yuan T, Krishnan JFrontiers in Physiology2021
MIR503HG Loss Promotes Endothelial-to-Mesenchymal Transition in Vascular Disease(Open Access) Monteiro JP, Rodor J, (...), Baker AHCirculation Research2021
MicroRNAs and Long Non-Coding RNAs as Potential Candidates to Target Specific Motifs of SARS-CoV-2(Open Access) Natarelli L, Parca L, Mazza T, Weber C, Virgili F, Fratantonio DNon-Coding RNA2021
Inflammation-Related Risk Loci in Genome-Wide Association Studies of Coronary Artery Disease(Open Access) Mauersberger C, Schunkert H, Sager HBCells2021
Cas9-expressing chickens and pigs as resources for genome editing in livestock(Open Access) Rieblinger B, Sid H, (...), Schusser BProceedings of the National Academy of Sciences2021
Plasma microRNA signature associated with retinopathy in patients with type 2 diabetes(Open Access) Santovito D, Toto L, (...), Cipollone FScientific Reports2021
Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation(Open Access) Dobersch S, Rubio K, (...), Barreto GNature Communications2021
MicroRNA-21–Dependent Macrophage-to-Fibroblast Signaling Determines the Cardiac Response to Pressure Overload(Open Access) Ramanujam D, Schön AP, (...), Engelhardt SCirculation2021
Genome editing for Duchenne muscular dystrophy: a glimpse of the future?(Open Access) Kupatt C, Windisch A, Moretti A, Wolf E, Wurst W, Walter MCGene Therapy2021
Impaired complex I repair causes recessive Leber’s hereditary optic neuropathy(Open Access) Stenton SL, Sheremet NL, (...), Prokisch HJ Clin Invest2021
Blood-based protein profiling identifies serum protein c-KIT as a novel biomarker for hypertrophic cardiomyopathy(Open Access) Sonnenschein K, Fiedler J, (...), Thum TScientific Reports2021
Long Non-coding RNA Aerrie Controls DNA Damage Repair via YBX1 to Maintain Endothelial Cell Function(Open Access) Pham TP, Bink DI, (...), Boon RAFrontiers in Cell and Developmental Biology2021
Noncoding RNAs in Vascular Diseases(Open Access) Jaé N, Dimmeler SCirculation Research2020
Prediction of single-cell gene expression for transcription factor analysis(Open Access) Behjati Ardakani F, Kattler K, (...), Schulz MHGigascience2020
Plasma circular RNA hsa_circ_0001445 and coronary artery disease: Performance as a biomarker(Open Access) Vilades D, Martínez-Camblor P, (...), de Gonzalo-Calvo DThe FASEB Journal2020
Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophyMoretti A, Fonteyne L, (...), Kupatt CNature Medicine2020
Functional investigation of the coronary artery disease gene SVEP1(Open Access) Winkler MJ, Müller P, (...), Kessler TBasic Research in Cardiology2020
ZNF354C is a transcriptional repressor that inhibits endothelial angiogenic sprouting(Open Access) Oo JA, Irmer B, (...), Leisegang MSScientific Reports2020
Inositol‐requiring enzyme‐1 regulates phosphoinositide signaling lipids and macrophage growth(Open Access) Hamid SM, Citir M, (...), Erbay EEMBO reports2020
Beyond the RNA-dependent function of LncRNA genes(Open Access) Ali T, Grote PElife2020
Autophagy unleashes noncanonical microRNA functions(Open Access) Santovito D, Egea V, (...), Weber CAutophagy2020
Precise Correction of Heterozygous SHOX2 Mutations in hiPSCs Derived from Patients with Atrial Fibrillation via Genome Editing and Sib Selection(Open Access) Sumer SA, Hoffmann S, (...), Rappold GAStem Cell Reports2020
Linc‐MYH configures INO80 to regulate muscle stem cell numbers and skeletal muscle hypertrophy(Open Access) Schutt C, Hallmann A, (...), Boettger TThe EMBO Journal2020
Should We Use Genetic Scores in the Determination of Treatment Strategies to Control Dyslipidemias?Lechner K, Kessler T, Schunkert HCurrent Cardiology Reports2020
Dynamic mRNP Remodeling in Response to Internal and External Stimuli(Open Access) Zarnack K, Balasubramanian S, (...), Sträßer KBiomolecules2020
MicroRNAs targeting the SARS-CoV-2 entry receptor ACE2 in cardiomyocytes(Open Access) Lu D, Chatterjee S, (...), Thum TJournal of Molecular and Cellular Cardiology2020
Agrin Promotes Coordinated Therapeutic Processes Leading to Improved Cardiac Repair in Pigs(Open Access) Baehr A, Umansky KB, (...), Tzahor ECirculation2020
Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions: A Scientific Statement From the American Heart Association(Open Access) Das S, Shah R, (...), Yin KCirculation: Genomic and Precision Medicine2020
Genetically determined intelligence and coronary artery disease risk(Open Access) Li L, Pang S, Zeng L, Güldener U, Schunkert HClinical Research in Cardiology2020
Non-coding RNAs: update on mechanisms and therapeutic targets from the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart(Open Access) Bär C, Chatterjee S, (...), Thum TCardiovasc Res2020
Small Things Matter: Relevance of MicroRNAs in Cardiovascular Disease(Open Access) Peters LJF, Biessen EAL, Hohl M, Weber C, van der Vorst EPC, Santovito DFrontiers in Physiology2020
Deep Characterization of Circular RNAs from Human Cardiovascular Cell Models and Cardiac Tissue(Open Access) Jakobi T, Siede D, (...), Dieterich CCells2020
Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosisSantovito D, Egea V, (...), Weber CScience Translational Medicine2020
Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function(Open Access) Stanicek L, Lozano-Vidal N, (...), Boon RACommunications Biology2020
EpiRegio: analysis and retrieval of regulatory elements linked to genes(Open Access) Baumgarten N, Hecker D, Karunanithi S, Schmidt F, List M, Schulz MHNucleic Acids Res2020
SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications(Open Access) Groß S, Jahn C, Cushman S, Bär C, Thum TJournal of Molecular and Cellular Cardiology2020
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction(Open Access) Trembinski DJ, Bink DI, (...), Boon RANature Communications2020
AntimiR-21 Prevents Myocardial Dysfunction in a Pig Model of Ischemia/Reperfusion Injury(Open Access) Hinkel R, Ramanujam D, (...), Engelhardt SJournal of the American College of Cardiology2020
Thymosin beta-4x LINCs SPAAR to its non-coding function(Open Access) Brandes RP, Oo JA, Leisegang MSCardiovasc Res2020
Statins Make a Difference in Acute Myocardial Infarction(Open Access) Baehr A, Hinkel R, Kupatt CJournal of the American College of Cardiology2020
Circular RNAs: A Novel Class of Functional RNA Molecules with a Therapeutic Perspective(Open Access) Santer L, Bär C, Thum TMolecular Therapy2019
Serum circular RNAs act as blood-based biomarkers for hypertrophic obstructive cardiomyopathy(Open Access) Sonnenschein K, Wilczek AL, (...), Thum TScientific Reports2019
Long noncoding RNAs in key cellular processes involved in aortic aneurysms(Open Access) Wu Z, Trenner M, Boon RA, Spin JM, Maegdefessel LAtherosclerosis2019
Linking obesity with abdominal aortic aneurysm development(Open Access) Eckstein H, Maegdefessel LEur Heart J2019